A member asked:

What can cause pancreatic cancer?

A doctor has provided 1 answer

Probable viral: Pancreas cancer starts out as an intraductal lesion similar to breast DTIC (dacarbazine). It smolders within the ductal system for 15-20 yrs before first signs of ductal wall invasion to become an early pancreatic carcinoma. The TAA that are expressed early are oncofetal in origin and are suppressed at birth to reappear in the tumor as the oncogenic protein. Transformation probably viral induced.

Answered 6/20/2019

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