A member asked:

What is duration time of novolog u-100 insulin, from start to finish type 1 diabetic for 44 years and been getting conflicting duration times from 30 minutes to 4 hours

3 doctors weighed in across 2 answers
Dr. Daniel Weiss answered

Specializes in Endocrinology

The : The onset of action (starts working) of this rapid acting Insulin is about 15 minutes. So it starts working then. It lasts up to 5 hours but has very little effect after 4 hours. These are general times and do vary from 1 person to the next. If you inject in lumpy areas where you have repeatedly been injecting over the years the onset of action may be slower (take longer). We know now that you do not need long needles, 4 millimeters is long enough for injection. See the links below to learn more about this and other insulins. You can do a test on yourself to see how long the NovoLog takes to work by treating a high sugar without eating. Discuss this with your endocrinologist.

Answered 10/3/2016

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Dr. Cayce Jehaimi answered

Specializes in Pediatric Endocrinology

Novolog, : Novolog, a short acting Insulin analogue, typically lasts about 3-3.5 hrs but some individuals can experience lasting effecs for up to 4-5 hrs. Its onset of action is within 15-20 minutes with peak levels around 1.5-2.5 hrs post injection. Hope this helps. Cayce t. Jehaimi, M.D., faap pediatric endocrinolog & diabetes the children's hospital of southwest florida fort myers, fl, usa.

Answered 10/4/2016

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