Is it possible to be weaned off the effexor and get my body back to normal? i have been taking effexor for years. a doctor recently increased my dosage to 300mg from 75mg. i have major digestive issues (constipation), i can't loose weight no matter what i

My : My patients seem to have a lot of problems with weight gain and increased blood pressure when their dose of Effexor (venlafaxine) gets into the range that it can impact more than one neurotransmitter. Weight gain is a frequent side effect of effexor (venlafaxine). Yes, Effexor (venlafaxine) can be weaned back down.

Serotonin : Serotonin discontinuation symptoms, associated with abrupt discontinuation of Effexor (venlafaxine) , could be related to it`s short half life. In most cases, this may be minimized by slowly tapering the dosage. Another strategy would be using a low dosage of a long acting ssri like fluoxetine.. The physical symptoms include problems with balance, gastrointestinal and flu-like symptoms, and sensory and sleep disturbances. Psychological symptoms include anxiety and/or agitation, crying spells, irritability and aggressiveness.