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A 39-year-old female asked:

Can i take zoloft (sertraline) and welbutrin with diet pills? such as xenadrine or hydroxycut? i need to lose 50 lbs. zoloft (sertraline) has made me gain a lot of weight. but i need it for ocd and depression.

2 doctor answers3 doctors weighed in
Dr. Heidi Fowler
Psychiatry 26 years experience
First, : First, this really needs to be discussed with your psychiatrist. I do not know your dose of medications. Selective serotonin reuptake inhibitors can be associated with weight gain. Just some things to discuss with your psychiatrist. Sometimes, Lexapro can be more weight neutral than zoloft. There are many studies that have shown weight loss with use of wellbutrin (bupropion) in depressed individuals who watched food intake and got a minimal amount of aerobic activity. Maybe there is room for an upward shift of your wellbutrin (bupropion) dose? Rather than adding another chemical into your system (xenadrine or hydroxycut) see if there could be some titrations with your current medications. Another thought might be use of medical acupuncture or hypnosis to assist with obtaining a heatlhy weight.
Dr. Donald Jacobson
A Verified Doctoranswered
41 years experience
Other diet options: Exercise and a healthy weight loss diet. In my practice i generally prescribe Diethylpropion er 75 mg around 2pm. I prescribe it because of the success i've had with it in patients on psychotropics. Other options include low dose topamax, (topiramate) but make sure you are aware of all the side effects. Green coffee bean extract can help as can ashwaghanda or garcinia cambogia.
Last updated Oct 3, 2016

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