Will fluoxetine start to make me feel better within a week?

Probably not: Fluoxetine, also known as prozac, (fluoxetine) has biochemical properties that lead it to last a long time. The down side of this is that it takes a longer time to be effective - for most people it takes 4-6 weeks. Other antidepressants in the same family like citalopram/celexa, escitalopram/lexapro and sertraline/zoloft take effect in a shorter period of time for most.

No: We usually tell pts 2-3 weeks for most antidepressants but 4-6 weeks for prozac (fluoxetine).