Yes: If your kidney stones back up your kidneys enough or cause recurrent infections, you could end up losing enough function to require going on dialysis or receiving a transplant.
Answered 3/2/2019
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Unusual but possible: Nephrocalcinosis means calcifications in the kidneys. As with any disease or metabolic problem there are many degrees of severity. This can be a component of a pathology called medullary sponge kidney, but it rarely progress to renal failure. Such patients need their blood calcium and parathyroid hormone checked.
Answered 7/26/2017
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