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A member asked:
What is the genetic reason for causing kleinfelter's?
3 doctors weighed in across 2 answers
Extra X in men: Klinefelter syndrome is usually caused by an extra x chromosome in males, changing their normal 46, xy chromosome constitution to 47, xxy. The extra x causes tall stature with an asthenic build, underdevelopment of the testis and infertility. Sometimes there is more than one x, like 48, xxxy, often causing intellectual disability. The extra chromosome is a chance occurrence.
Answered 10/3/2016
6.3k views
Klinefelters: This disease can be detected by genetic testing with a mutation of XYY instead of XY. It can present with short stature, cognitive difficulties and infertility.
Answered 9/5/2018
282 views
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