A 47-year-old member asked:
what is the genetic reason for causing kleinfelter's?
2 doctor answers
Dr. Golder Wilson answered
Specializes in Clinical Genetics
Extra X in men: Klinefelter syndrome is usually caused by an extra x chromosome in males, changing their normal 46, xy chromosome constitution to 47, xxy. The extra x causes tall stature with an asthenic build, underdevelopment of the testis and infertility. Sometimes there is more than one x, like 48, xxxy, often causing intellectual disability. The extra chromosome is a chance occurrence.
Answered on Oct 3, 2016
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