A 47-year-old member asked:
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what is the genetic reason for causing kleinfelter's?

2 doctor answers
Dr. Golder Wilson
Specializes in Clinical Genetics
Extra X in men: Klinefelter syndrome is usually caused by an extra x chromosome in males, changing their normal 46, xy chromosome constitution to 47, xxy. The extra x causes tall stature with an asthenic build, underdevelopment of the testis and infertility. Sometimes there is more than one x, like 48, xxxy, often causing intellectual disability. The extra chromosome is a chance occurrence.
Answered on Oct 3, 2016
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Dr. Ivy Fisher
43 years experience Pediatrics
Klinefelters: This disease can be detected by genetic testing with a mutation of XYY instead of XY. It can present with short stature, cognitive difficulties and infertility.
Answered on Sep 5, 2018
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1 comment
Dr. Al Hegab
Dr. Al Hegab commented
39 years experience Allergy and Immunology
XXY chromosomes, rather
Sep 5, 2018

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Related questions:

A 34-year-old member asked:
Dr. Gurmukh Singh
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More than one x: It is a genetic anomaly in which a phenotypic male has more than one x chromosome, in addition to the y chromosome. The disorder is associated with p ... Read More
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A 37-year-old member asked:
Dr. Randolph Thomas
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Chromosomal disorder: Klinefelter syndrome is also known as XXY condition. Men with this condtion have an extra x chromosome in most of their cells. Not all men with the c ... Read More
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Klinefelter's: A boy is born with an extra copy of the x chromosome. This is what causes it.
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