For a prostate cancer patient, can he start lhrh treatment first to see the effect, then go for orchirectomy? any drawback to do this?

Yes, you can do it: No drawback. Absolutely he can start with lhrh agonist like Lupron (leuprolide) plus minus Casodex for instance and reserve the option of orchiectomy for the future-if needed. That's what we usually do actually most of the time. No drawback with that plan. Discuss with your doctor in detail.

No drawback: This is the preferred approach for the majority of patients.

No: There is no drawback. The effect would be similar either way, but lhrh injection would allow for intermittent therapy if appropriate. If permanent hormone deprivation is desired, orchiectomy can be performed at a later time.

Orchiectomy is the: Least costly way to treat advanced prosca. Lhrh shots are expensie, but can be stopped, and there is a chance that testicular function can be resumed...Not usually necessary in advanced disease, but a desireable feture for short course testicular blockade in intermediate risk disease.