A member asked:

Are there any drugs that may cause leg claudication?

8 doctors weighed in across 2 answers

Sort of: The most common cause of leg cramping from medication is likely the family of statin drugs used to lower cholesterol. Monitoring of liver and muscle enzymes is common with statins. With normal lab results changing doses or brands can improve the muscle cramping.

Answered 3/2/2014

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Yes: Nicotine if you are a smoker.

Answered 4/18/2012

5.9k views

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