A member asked:

Toprol (metoprolol) xr lasts 24 hours right? and omeprazole delayed release, how long does that one last?

A doctor has provided 1 answer

> 24 hours: From the professional monograph: duration of secretion inhibition is up to 72 hours; inhibition is 50% of maximum at 24 hours. Inhibition increases with repeated daily dosing, reaching steady-state plateau at 4 days. After discontinuance, gastric secretion gradually increases over 3–5 days.

Answered 5/24/2020

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