The former: Isotretinoin (iso) has a half life of 20 hrs at most. After discontinuation, it is eliminated completely after a month. There are analogies to fat soluble vitamin a and metabolites of iso that saturate fatty tissues that might be confusing. The nih suggests it is gone by a month. See <a href="<a href="http://dailymed.Nlm.Nih.Gov/dailymed/archives/fdadruginfo.Cfm?Archiveid=8655" rel="nofollow" targ.
Answered 8/3/2017
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