Could i replace ava pro with lisinopril?

Yes: Especially if you have had a cough or difficulty with lisinopril.

Avapro-lisinopril: The answer to your question is "yes". Avapro (irbesartan) is a type of angiotensin receptor blocker (arb) drugs and Lisinopril is a member of the ace-inhibitor (a) class of drugs. Both reduce not only BP but protein in the urine as well. Unless you have a cough from the a, there is no compelling reason to go from an arb to an a. Speak to your physician for more information in your case.