A 46-year-old member asked:
What is leukodystrophy?
1 doctor answer • 4 doctors weighed in
Dr. Bennett Machanicanswered
Neurology 47 years experience
Childhood: This is a class of hereditary disorders affecting the white matter of the brain mainly presenting in childhood. The diseases may vary in extent and pace, but often affect walking, cognition, and may be associated with epilepsy. More information may be found on mayo clinic site or www.Aan.Com.
Created for people with ongoing healthcare needs but benefits everyone.
5.6k viewsReviewed >2 years ago
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A 32-year-old member asked:
What are the tests for leukodystrophy?
1 doctor answer • 1 doctor weighed in
Dr. Colin Kerranswered
Family Medicine 46 years experience
Leukodystrophy tests: Neurodevelopmental tests demonstrate the following findings in patients with infantile or early juvenile metachromatic leukodystrophy:
•loss of previously achieved developmental milestones
•tremors
•truncal ataxia
•hyperreflexia progressing to hyporeflexia
•hypotonia
•gait abnormalities
•optic atrophy
neurocognitive tests demonstrate other abnormalities.
Created for people with ongoing healthcare needs but benefits everyone.
5.8k viewsAnswered >2 years ago
A 42-year-old member asked:
What are the symptoms of leukodystrophy?
1 doctor answer • 1 doctor weighed in
Dr. Colin Kerranswered
Family Medicine 46 years experience
Leukodystrophy signs: •gait disturbances
•memory deficits
•seizures (may be present)
•loss of motor developmental milestones
•decreased attention span
•speech disturbances
•decline in school performance
the early juvenile form includes the following:
•gait disturbances
•tremors
•clumsiness
•loss of previously achieved skills
•intellectual decline
•behavioral changes
•seizures (possible)
the late juvenile and adult for.
Created for people with ongoing healthcare needs but benefits everyone.
5.8k viewsAnswered >2 years ago
A 34-year-old member asked:
What can you tell me about leukodystrophies?
1 doctor answer • 3 doctors weighed in
Dr. Colin Kerranswered
Family Medicine 46 years experience
Leukodystrophy: Metachromatic leukodystrophy (mld) is a genetic disorder that affects nerves, muscles, other organs, and behavior. It slowly gets worse over time.
Mld is usually caused by the lack of an important enzyme called arylsulfatase a. Because this enzyme is missing, chemicals called sulfatides build up in and damage the nervous system, kidneys, gallbladder, and other organs. http://www.ncbi.nlm.nih.gov/p.
Created for people with ongoing healthcare needs but benefits everyone.
5.8k viewsReviewed >2 years ago
A 41-year-old member asked:
What are the tests for leukodystrophies?
1 doctor answer • 1 doctor weighed in
Dr. Colin Kerranswered
Family Medicine 46 years experience
Leukodystrophy tests: Neurodevelopmental tests demonstrate the following findings in patients with infantile or early juvenile metachromatic leukodystrophy:
•loss of previously achieved developmental milestones
•tremors
•truncal ataxia
•hyperreflexia progressing to hyporeflexia
•hypotonia
•gait abnormalities
•optic atrophy
neurocognitive tests demonstrate other abnormalities.
Created for people with ongoing healthcare needs but benefits everyone.
5.8k viewsAnswered >2 years ago
A 41-year-old member asked:
What is the treatment for leukodystrophy?
1 doctor answer • 2 doctors weighed in
Dr. Colin Kerranswered
Family Medicine 46 years experience
Leukodystrophy Rx: Treatment
there is no cure for mld. Care focuses on treating the symptoms and preserving the patient's quality of life with physical and occupational therapy.
Research is studying techniques to replace the missing enzyme (arylsulfatase a).
http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0002185/.
Created for people with ongoing healthcare needs but benefits everyone.
5.8k viewsReviewed >2 years ago
Last updated Sep 11, 2019
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