One of the side effects of gleevec (imatinib) is bone pain. i can't take nsaids.i am on a combination of duragesic and vicodan.any suggestions other than narcs?

Adjuvant therapy: There is good evidence that shows anti-epileptic medications, Gabapentin and Lyrica (pregabalin) specifically, can work in conjunction with opioids in reducing pain as they work on different pain receptors. Cymbalta has also been approved for various pain conditions including back pain, osteoarthritis pain, fibromyalgia, diabetic peripheral neuropathy, etc.

It's Complicated!: Since the combination of imatinib (gleevec) and Acetaminophen may increase the chance of liver toxicity and nsaids aren't an option for you, pain medicine options are somewhat limited. I strongly recommend that you speak to your oncologist for assessment and guidance on this issue. He/she will have specific options for your unique situation. Best of luck!