Troublesome disease: With regard to scleroderma, scl-70 is a topoisomerase-1-antibody and this is present in about 30-35% of those with diffuse disease. Scleroderma is most noticeable on the skin but it can affect virtually any organ/system including lung, heart, eye, kidneys, gastrointestinal tract etc. Treatment is difficult and it is advisable that she sees a rheumatologist. I wish her the best of luck.
Answered 12/9/2013
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