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A member asked:
What is the relationship between adh (vasopressin) and aqp2 in urinary system?
A doctor has provided 1 answer
Signal-response.: Adh, or vasopressin, is a hormone released by the posterior pituitary gland when the body wishes to conserve water. Aquaporin 2 (aqp2) channels in the kidney are activated by adh, which reabsorb water back into the bloodstream, concentrating and decreasing the volume of urine. Mutations in aqp2 can lead to diabetes insipidus, where large volumes of urine are released.
Answered 3/30/2018
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During fluid deprivation test, the ADH (vasopressin) level dropped down to 1/3 of pre test level and below reference values. Is that a sign of diabetes insipidus?
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