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What is no blast seen means in peripheral blood smear?

3 doctors weighed in across 2 answers

It's a good thing!: Blasts are immature blood cells. They normally grow and mature in the marrow and then the more adult cells are extruded into the blood stream to perform their function. So, not seeing them in the blood film is a good sign we look for when evaluating someone with a blood disorder.

Answered 7/10/2018

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Good sign/no problem: No blasts in the peripheral blood smear is a normal finding. This means your bone marrow/peripheral blood transfer of cells is working properly, with no immature forms getting into the blood. If there were blasts there, a work-up for a possible leukemia or lymphoma would have to be done. Sometimes blasts in the blood may be from something else putting a strain on the marrow, but none is good.

Answered 7/10/2018

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