A member asked:

What does high neutrophils and low lymphocytes in a patient with gastroenteritis and pancreatitis indicate? could this be a result of an autoimmune condition? on another occasion in the same patient, what about normal neutrophils but low lymphocytes prese

5 doctors weighed in across 2 answers
Dr. Stuart Hickerson answered

Specializes in Family Medicine

Neutrophils: Both conditions are acute inflammatory conditions and would cause this picture- high neutrophils and low lymphocytes. This is what is known as a left shift and is commonly seen. Although an autoimmune process may be an underlying cause this specific WBC reaction is not an indication of autoimmunity.

Answered 8/24/2017

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Dr. Thomas Klein answered

Specializes in Allergy and Immunology

See below: Elevated neutrophils and a low lymphocyte count is also called a "shift to the left." it could be caused by infection and also steroids. Autoimmune conditions should not be the cause. Regarding the same patient and low lymphocytes with a normal neutrophil count i would wonder about their immunoglobulin levels to see if they have an immune deficiency.

Answered 1/5/2019

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