Neutrophils: Both conditions are acute inflammatory conditions and would cause this picture- high neutrophils and low lymphocytes. This is what is known as a left shift and is commonly seen. Although an autoimmune process may be an underlying cause this specific WBC reaction is not an indication of autoimmunity.
Answered 8/24/2017
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See below: Elevated neutrophils and a low lymphocyte count is also called a "shift to the left." it could be caused by infection and also steroids. Autoimmune conditions should not be the cause. Regarding the same patient and low lymphocytes with a normal neutrophil count i would wonder about their immunoglobulin levels to see if they have an immune deficiency.
Answered 1/5/2019
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