A member asked:

How do b-cell deficiencies people benefit from artificial passive immunotherapy?

2 doctors weighed in across 2 answers

Definitions: B cell deficiencies are characterized by absent or deficient production of specific antibodies to substances, for example vaccines. For these patients to be protected from infections, a pool of antibodies from healthy donors (ivig) is given. Passive immunotherapy means giving antibodies, the can be ivig or specific antibodies against a microbe, for example anti-tetanus antibodies.

Answered 11/29/2011

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Dr. Thomas Klein answered

Specializes in Allergy and Immunology

IVIG: Intravenous immunoglobulins (ivig) is passive therapy whereby an infusion provides the necessary immune proteins to fight infection if there is a b cell deficiency or a deficiency in b cell derived immune proteins. Ivig infusions contain immunoglobulins that provide temporary immunity. The infusions have to be repeated every 4 weeks or so. They can even be given subcutaneously in the home.

Answered 12/2/2012

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