Can prozac (fluoxetine) cause manic depression?

Maybe: Prozac (fluoxetine) is an antidepressant. Many antidepresants including Prozac (fluoxetine) can cause patients who have bipolar disorder or who are prone to symptoms of bipolar, to develop bipolar symptoms. The best way to avoid this is to work with a psychiatrist who can provide meds for both the depressive and the manic symptoms of bipolar moods.

Sometimes: To treat bipolar depression, antidepressants like Prozac (fluoxetine) can sometimes be added to mood stabilizing agents, but since they can trigger a switch to mania, patients need to be closely monitored.

Prozac (fluoxetine): Prozac (fluoxetine) does not cause manic depression, but can trigger manic episodes in bipolar patients.

Likely not: I have never heard of Prozac (fluoxetine) causing mania or depression in anyone who suffers from manic depression. Manic depression is medicated by mood stabilizers such as lithium or depakote, and not Prozac (fluoxetine) which is typically used for depression alone, and not mania.