Is insulin resistance reversible? if so, what can one do to reverse it?

YES,INSULIN RESISTAN: Insulin ressistance(ir) is a survival trait that allowed your ancesters to survive famines, and is caused by the loss of the phosphate group on the activated vitamin b-6(p-5-p) or the lack of p-5-p in your diet as occurs in a famine. The phosphate loss is caused by eating sugar which de destroys p-5-p. This (ir) saves the glucose for the brain by resisting glucose entry into the rest of the body.

To some extent: Genetic programming + environmental factors, like obesity, cause Insulin resistance (ir). Even in thin girls & women with pcos, they have ir. Certain ethnic groups also have ir like african and native american. Obesity exacerbates ir making more likely to get diabetes, heart disease, high blood pressure, etc. Metformin and lifestyle change can reduce ir, postponing/preventing complications of ir.