A member asked:

How can nsaids cause renal failure?

5 doctors weighed in across 2 answers

Prostaglandins: Nsaids inhibit prostaglandins, the bad ones that cause inflammation but also the good ones that help make your stomach coating and help maintain good blood flow in the kidneys. Over time, chronic NSAID use can cause kidney failure.

Answered 6/10/2014

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Dr. Fred McCurdy answered

Specializes in Pediatric Nephrology and Dialysis

NSAIDS: They can reduce blood flow through the kidneys and they can cause inflammation within the kidney. Here's a good place to find out more: http://www.Uptodate.Com/contents/nsaids-acute-kidney-injury-acute-renal-failure-and-nephrotic-syndrome.

Answered 11/22/2013

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