A member asked:

What is a more effective treatment for cold sores, zovirax (acyclovir) or abreva?

8 doctors weighed in across 3 answers

Zovirax (acyclovir): Zovirax (acyclovir) is more effective but laser treatment will help to immediately relieve the pain and heal the sore quickly.

Answered 4/4/2016

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Zovirax (acyclovir): Antiviral medication effective against herpes virus.

Answered 12/19/2016

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Dr. Hunter Handsfield answered

Specializes in Infectious Disease

Docosanol (Abreva) doesn't work at all against oral herpes (cold sores). Acyclovir (Zovirax) ointment is better, but still not highly effective for most persons. The best treatment by far is a single large oral dose of valacyclovir (2 grams) taken immediately after start of an outbreak.

Answered 8/5/2021

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