Lowers leptin: Generally, dieting will decrease circulating levels of leptin. Without leptin activating receptors in the hypothalamus, the body will think that it is in a constant state of starvation due to the lack of sufficient energy stores. This will lead to an increase in levels of ghrelin causing a stimulation of hunger. Fasting in order to lose weight will cause ghrelin levels to remain high, feel hungry.
Answered 10/11/2011
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