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A 35-year-old member asked:

how can i find out if i have a normal leptin level?

2 doctor answers3 doctors weighed in
Dr. Vasu Brown
Integrative Medicine 34 years experience
Men1-5ng/wmen7-13ng: ]in healthy individuals, baseline leptin levels are between 1-5 ng/dl in men and 7-13 ng/dl in women. Human leptin is a protein of 167 amino acids. It is manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.
Dr. Paul Bressman
Vascular Surgery 50 years experience
Biochemical markers: There is no known standardized test at this time. Leptin levels are . The following findings correlate with leptin resistance: morning blood sugar > 95; hbac1n >5.6; positive microalbumin test; elevated LDL and triglycerides with a low hdl; low testosterone levels in men; non alcohollic fatty liver disease (ultrasound test); polycystic ovarian syndrome in women; central obesity pattern.

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A 42-year-old member asked:

Which fruits have leptin?

2 doctor answers4 doctors weighed in
Dr. Vasu Brown
Integrative Medicine 34 years experience
Fish-rich diet: Digestive tract cannot absorb leptin, so even if you could find a food rich in leptin it wouldn't help - forget about finding foods rich in leptin. The body has to create it's own leptin. And as you lose weight, leptin levels drop, because fat itself causes the body to produce more leptin. Latest study suggests that a fish-rich diet somehow makes your body more sensitive to leptin, &help wt loss.
A 25-year-old member asked:

Is there an after effect of a 'leptin deficiency'?

2 doctor answers3 doctors weighed in
Dr. Vasu Brown
Integrative Medicine 34 years experience
Thyroid issues: Thyroid function is closely related to leptin's secretion by the adipose tissue. In states of leptin-deficiency, the circadian rhythm of TSH is altered, leading to central hypothyroidism in animal models. In humans, central hypothyroidism has also been described in rare cases of congenital leptin deficiency.
A 31-year-old member asked:

What are the differences between grehlin and leptin?

2 doctor answers3 doctors weighed in
Dr. Vasu Brown
Integrative Medicine 34 years experience
Satiation vs hunger: Leptin is for satiation vs ghrelin for hunger. Leptin is a mediator of long-term regulation of energy balance, suppressing food intake and thereby inducing weight loss. Ghrelin on the other hand is a fast-acting hormone, seemingly playing a role in meal initiation.
A 36-year-old member asked:

Can we make drugs based on leptin for satiety?

1 doctor answer1 doctor weighed in
Dr. Paul Harper
General Surgery 52 years experience
Maybe: Some day, but as far as i know, not even close.
A 32-year-old member asked:

What are the risks of having low leptin levels?

1 doctor answer1 doctor weighed in
Dr. Terry Simpson
General Surgery 35 years experience
We don't know: New field and hard to know. They are not commonly measured so we don't have reference ranges.

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Last updated Jul 16, 2013

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