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A 23-year-old member asked:

What effect does dieting have on leptin levels?

2 doctor answers2 doctors weighed in
Dr. Cayce Jehaimi
Pediatric Endocrinology 22 years experience
Lowers level: If dieting is intended to lower fat content, then there should be expected drop in leptin levels as this hormone (cytokine) is produced by the fat cells (adipocytes).
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Vasu Brown
Integrative Medicine 35 years experience
Lowers leptin: Generally, dieting will decrease circulating levels of leptin. Without leptin activating receptors in the hypothalamus, the body will think that it is in a constant state of starvation due to the lack of sufficient energy stores. This will lead to an increase in levels of ghrelin causing a stimulation of hunger. Fasting in order to lose weight will cause ghrelin levels to remain high, feel hungry.
Created for people with ongoing healthcare needs but benefits everyone.

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Last updated Dec 23, 2014

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