A 51-year-old member asked:
Is it possible for cancer cells to repair the DNA damaging effects of melphalan?
1 doctor answer
Dr. Addagada Rao answered
55 years experience in General Surgery
Interrupts DNA &RNA: Melphalan or Alkeran (melphalan) is nitrogen mustard derivative by alkalating n7 position of guanine interferes dna and ran synthesis in tumor cell, if the tumor is resistant to drug means tumor cell is repairing damage.
Answered on Oct 3, 2016
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