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A member asked:
Can an od of 1600mg to 3200mg on diphenhydramine effect the liver or any other organs?
A doctor has provided 1 answer
See a doctor now!: Dphm (aka benadryl): "severe" symptoms occur at the critical dose limit of 1 gram=1000mg. Although the frequency of delirium/psychosis, coma and seizures can occur. "moderate" symptoms (300mg or more) include isolated & spontaneously resolving agitation, confusion, hallucinations & ekg abnormalities. It is metabolized via cytochrome p450 2d6 isoenzyme in the liver.
Answered 7/3/2017
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