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A member asked:
Is tay-sachs disease a result of nondisjunction during meiosis?
A doctor has provided 1 answer
No: Tay-sachs d. Inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. The problems lies in enzyme gene mutation (hexa) located in lysosomes, no gm2 gangliosids break down.
Answered 2/8/2017
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