Is it safe to get a pap smear if you have an anal abscess?

Yes, but get Rx.: This should be safe as it really is a swab of the surface of the cervix, and its mucus with a wooden swab spatula, and should not disrupt the abscess. However, such a lesion should get treated since it could rupture at any time and possibly spread infection, and this as well as hemorrhoids could lead to complications like anal cancer which is more common in women, so get it treated ahead of time.