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A 33-year-old member asked:

can i have a glass of wine with duloxetine?

2 doctor answers4 doctors weighed in
Dr. Mark Reynolds
Psychiatry 33 years experience
Yes, with caution.: You should not combine Cymbalta (duloxetine) with chronic or heavy alcohol use due to possible increase risk to the liver. Caution is always advised when combining drugs that act in the brain, in this case alcohol and cymbalta (duloxetine).
Dr. Pamela Pappas
Psychiatry 42 years experience
Not at same time: You should take your duloxetine with water, not wine or other kinds of alcohol. While on duloxetine, i agree with dr. Reynolds' advice to be very cautious in your drinking.

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A 29-year-old member asked:

Are generic versions of duloxetine as safe as the brand name drug?

2 doctor answers2 doctors weighed in
Dr. Kevin Considine
Family Medicine 30 years experience
Yes: Yes generic versions of duloxetine should be safe along with any other generics although i'm not sure that a generic of duloxetine is available yet?
CA
A 46-year-old member asked:

Does it make a difference whether I take my cymbalta (duloxetine) in the night or the morning?

4 doctor answers7 doctors weighed in
Dr. Barbara A Majeroni
Specializes in Family Medicine
Morning is better: Taken in the evening, Cymbalta (duloxetine) can cause insomnia, so it is better to take it in the morning.
CA
A 27-year-old member asked:

How quickly is it safe to increase my dose of cymbalta (duloxetine)?

3 doctor answers6 doctors weighed in
Dr. Leonard Raucher
Specializes in Family Medicine
1 weeks: You may safely increase Cymbalta (duloxetine) on a weekly basis.
CA
A 37-year-old member asked:

Will cymbalta (duloxetine) make me feel better right away?

1 doctor answer3 doctors weighed in
Dr. Alfredo Soto
Psychiatry 26 years experience
No: The effects of Cymbalta (duloxetine) will take from 1 week to 1 month depending on why you are using it. It can help symptoms of pain in 1-2 weeks, and depression in 1-4 weeks. It usually takes longer for Cymbalta (duloxetine) to help symptoms of anxiety.
A 48-year-old member asked:

Is glass of wine ok to have on duloxetine?

2 doctor answers13 doctors weighed in
Dr. William Holmes
Child Psychiatry 34 years experience
Probably: You would want to be cautious because you could get added sedation with the combination of alcohol and duloxetine. You may find that you do not tolerate the same amount of alcohol as in the past due to the medication.

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Last updated Sep 13, 2019

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