If you have an allergy to cats, will you have an allergy to all animals in the cat family?

Cat allergy info : Possibly. There can be some cross-reactivity between big cats and house cats, and I have had patients who work with big cats report that they were affected, so it's possible. The antigens probably are not exactly the same, so it would likely require some regular exposure--working in a zoo or preserve, to get symptoms. A person with severe cat allergies might want to pick a career without exposure.