Can clindamycin be used to treat upper respiratory infection?

Yes: Clindamycin mainly covers anaerobic infections. These "anaerobes" are the bacteria that can reside in a patients mouth. Clindamycin can be used in aspiration pneumonias and in lung abscesses (a pocket full of pus in the lungs).

Bacterial Infection: Clindamicin may treat an upper respiratory infection, but only those that are caused by bacteria. The majority of uris are viral, so most will not respond to this medicine.