A member asked:

Is there a difference between tylenol (acetaminophen) with codeine #3 and tylenol (acetaminophen) with codeine #4?

5 doctors weighed in across 2 answers

Different dosages of: The tylenol (acetaminophen) 3 has 30 mg codiene and tylenol (acetaminophen) 4 has 60 mg codiene.

Answered 3/29/2019

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Dr. Alvin Lin answered

Amount of Codeine: Both t#3 & t#4 contain 300mg Acetaminophen (tylenol). But while t#3 also contains 30mg of codeine, t#4 contains 60mg or twice as much. Fyi maximum daily dose of Codeine for pain purposes is 360mg; for Acetaminophen the maximum dose has been lowered from 4, 000mg daily down to 3, 000mg daily assuming you have no liver issues and don't drink alcohol to excess.

Answered 2/6/2019

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