A member asked:

My thyroid scan/uptake shows mild hyperthyroidism, but blood-work shows hypothyroidism. does this happen often? what should i do?

3 doctors weighed in across 2 answers

Reverse T3 (liothyronine): Thyroid scan/uptake shows mild hyperthyroidism, but blood-work shows hypothyroidism. Thyroid gland is working hard but producing ineffective hormone. Test for reverse t3 (liothyronine). Thyroid hormone replacement is reasonable. Possible mutations in the sbp2 gene: abnormal thyroid function tests, low triiodothyronine (t3 (liothyronine)), high thyroxine (t4) and reverse t3 (liothyronine), and slightly elevated thyrotropin.

Answered 7/4/2013

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Antibodies: You probably have several types of thyroid antibodies floating around your system. Some cause hyperthyroidism while others may block their effect on the thyroid receptor. Treat your levels- if you're hypo - treat with synthroid (thyroxine). Monitor function and antibody levels over time.

Answered 8/2/2012

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