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A 25-year-old member asked:

What are the causes of crohn's disease and ulcerative colitis?

2 doctor answers8 doctors weighed in
Dr. Vivek Huilgol
Gastroenterology 36 years experience
Genes+environment : A combination of genetic predisposion (for example Crohn's is more common in ashkenazi jews), life events (eg appendectomy increases one and decreases the other), and environmental influences (eg smoking increases Crohn's and decreases severity of uc...). Bet you didn't expect the latter! as knowledge increases more precise factors are identified.
Dr. Jay Stylman
General Surgery 39 years experience
Immunologic: While no one knows the exact cause of inflammatory bowel disease, there is an alteration in the immune system, causing our own antibodies to target our intestinal tract. The extent of inflammation is variable, and there may be significant repercussions in both of these diseases.

Similar questions

A 41-year-old member asked:

What are symptoms of Crohn's disease and ulcerative colitis?

2 doctor answers5 doctors weighed in
Dr. Kirpal Singh
General Surgery 25 years experience
See below : Ibd usually presents with lots of diarrhea (mucousy, bloody or just loose). Some have bad pain, cramping, nausea, wt loss etc.
A 44-year-old member asked:

Are ulcerative colitis and Crohn's disease hereditary?

3 doctor answers8 doctors weighed in
Dr. Jason Bodzin
General Surgery 52 years experience
Somewhat: There are numerous families where there are children and /or grandchildren, cousins, etc. With these diseases. If both parents have ibd, the incidence is around 50% in the kids. Otherwise about 20% of patients will have a first degree relative with ibd. So you do the math! it isn't exactly hereditary, but there a familial incedence. By the way, the kids of colitis patients often have crohn's.
A 40-year-old member asked:

Which is a more serious disease: Crohn's or ulcerative colitis?

1 doctor answer1 doctor weighed in
Dr. Laurence Badgley
General Practice 54 years experience
UC: Question as to which is more serious, Crohn's or Ulcerative Colitis, misses the point that these are different intensities of disorder along a spectrum of manifestation wherein intestinal smooth muscle function is hyperdynamic due to neurologic autonomic system impingement & over-stimulation. Ulcerative Colitis represents greater intensity of these dysfunctions; involving inflammation & bleeding.
A 31-year-old member asked:

What is the cause of chrons vs ulcerative colitis?

1 doctor answer2 doctors weighed in
Dr. Jeffrey Cohen
Colon and Rectal Surgery 30 years experience
Genetic: Current belief that these are both genetic diseases related to immune modulation.
A 44-year-old member asked:

How does IBS differ from Crohn's disease or ulcerative colitis?

2 doctor answers6 doctors weighed in
Dr. Arthur Heller
Gastroenterology 44 years experience
Apples and oranges: Ibs: irritable bowel syndrome is not inflammation. Anatomy normal, but functional abnormality. Can occur after a GI infection.Sx occur on and off. Uc and cd are inflammatory; chronic, can have mild or severe consequences/complications. Uc: inflamed lining of colon, starting in rectum, variable extent. Cd-full thickness infl of bowel from lips to anus, can skip areas ibd rx meds +/- surgery.

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Last updated Apr 7, 2016
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