A 47-year-old member asked:
Can you tell me physically and structurally what is the difference between immunoglobulin g and m etc.?
1 doctor answer • 2 doctors weighed in
Allergy and Immunology 21 years experience
Simply Put: Both IgG and IgM are immunoglobulin proteins with a roughly "Y" shape which binds to an antigen (foreign substance in the body) at one end and a cellular receptor at the other end. The principal differences lie in how and when they form. IgM is made early in infections and form pentamers. IgG is made later in infections, is more specific, and circulates as monomers.
3.8k viewsReviewed >2 years ago
Last updated Apr 10, 2019
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