A member asked:

Can you explain the differences between celiac disease, gluten intolerance, and wheat or gluten allergy?

5 doctors weighed in across 3 answers

Intol. isn't allergy: Celiac disease (gluten allergy) is a big allergic reaction to gluten (a protein in grains such as wheat, barley, rye, etc...). Wheat allergy includes allergy to non-gluten parts or wheat. Gluten intolerance is not an allergic reaction, but does lead to tummy symptoms such as gassiness, loose stools, etc... Gluten intolerance does not cause damage to the intestinal lining like celiac disease does.

Answered 10/3/2016

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Celiac disease: Celiac disease and gluten intolerance are the same disease, but gluten oe wheat allergy is ige mediated allergy.

Answered 9/28/2016

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Differs considerably: Consider wheat as a composite of many proteins all of could trigger a simple allergic response like hives. Intolerance is similar. The reaction clears when the protein trigger is gone. In celiac disease the body produces antibodies to various gluten proteins that mistakenly attack intestinal tissue & cause tissue damage. That tissue injury can continue as long as there are circulating antibodies

Answered 2/20/2020

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