A member asked:

What triggers puberty?

5 doctors weighed in across 2 answers
Dr. Cayce Jehaimi answered

Specializes in Pediatric Endocrinology

Still largely unknow: We still do not know precisely, yet certain hormonal chemicals are well know to play a major role such as leptin, gpr54, kisspeptin and melatonin.

Answered 5/7/2014

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Genetics leptin: Genetics is one factor. Achieving a certain body weight, especially body fat. Adipose makes leptin, which is a signal to the brain to start making reproductive hormones. Girls with low body weight (eg gymnasts, balarinas) often have a delayed puberty.

Answered 3/12/2014

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