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A 58-year-old female asked:

is it ok to take a "vacation" from femara (letrozole)?

2 doctor answers6 doctors weighed in
Dr. Jeff Livingston
Obstetrics and Gynecology 22 years experience
Depends why: The answer will depend why you are taking it. If you are using this for infertility and ovulation induction then yes it is ok. If you are using this for breast cancer then i would have to defer to the oncologists and breast surgeons for a reliable answer.
Dr. Liawaty Ho
Hematology and Oncology 23 years experience
Discuss with you MD: It depends on what you mean by "vacation". How long you are thinking to stay off the femara (letrozole)?. Since i don't know any other information- such as the staging- the goal of therapy, your tolerance etc, i would suggest you to discuss this matter with your oncologist.

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A 40-year-old member asked:

Can you take femara (letrozole) with mucinix?

2 doctor answers2 doctors weighed in
Dr. Quang Nguyen
Specializes in Endocrinology
Yes: You can take both.
A 34-year-old member asked:

Have there been any adverse interactions between femara (letrozole) and grapefuit?

2 doctor answers4 doctors weighed in
Dr. Barry Rosen
General Surgery 34 years experience
Indirectly: There is a substance in grapefruit that disables the enzyme responsible for metabolizing estrogen in our bodies; therefore, eating grapefruit may increase the body's levels of estrogen. Femara (letrozole) is used to inhibit the production of estrogen in the body as a treatment for hormone-sensitive breast cancer. Therefore, eating grapefruit in these circumstances may counteract what you are treating.
CA
A 27-year-old member asked:

Is letrozole different from tamoxifen?

2 doctor answers4 doctors weighed in
Dr. Barry Rosen
General Surgery 34 years experience
Yes.: Tamoxifen is a selective estrogen receptor modulator; Letrozole is an aromatase inhibitor. Both drugs are used to treat hormone-positive breast cancer patients. However, Letrozole can only be used after menopause. Furthermore, tamoxifen can also be used to prevent breast cancer in high-risk women.
CA
A 35-year-old member asked:

What are some alternate medicines for femara (letrozole)?

2 doctor answers7 doctors weighed in
Dr. Deanna Attai
A Verified Doctoranswered
A US doctor answeredLearn more
See full answer: Currently the alternatives to Femara (also known as letrozole) are Arimidex (anastrozole) and Aromasin (exemestane). All 3 belong to a class of medications known as aromatase inhibitors and can help reduce the risk of breast cancer recurrence. Another type of medication, tamoxifen, is known as a selective estrogen receptor modulator, or serm - it is primarily used in premenopapusal women.
A 44-year-old member asked:

What are some possible side effects of femara (letrozole)?

2 doctor answers3 doctors weighed in
Dr. Barry Rosen
General Surgery 34 years experience
Hot flashes, etc.: The most common side effects of Femara (letrozole) include hot flashes, joint pain, headaches, back pain, and increased sweating. Less common side effects include nausea, vomiting, weight changes, and constipation. Despite this laundry list of possibilities, in reality, most people tolerate Femara (letrozole) very well.

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