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A 31-year-old member asked:

Is it possible to have a lyme infection with a negative igg but positive igm?

1 doctor answer2 doctors weighed in
Dr. James Ferguson
Pediatrics 47 years experience
Yes: Igm is the immunoglobulin noted for coming out early in response to any illness, it fades over time while igg come out a bit later and stays up longer. If you have a positive IgM it indicates a early response, while igg would probably show up in a few months at which point the IgM would have declined.
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Similar questions

A 48-year-old member asked:

Igm is negative but IgG is positive for Lyme disease, what to do?

1 doctor answer2 doctors weighed in
Dr. Michael Rupp
Allergy and Immunology 22 years experience
Old Infection: This most likely means you had an old infection with lyme disease. Our bodies make IgM early in an infection and IgG later. Even once the infection is gone there will be detectable IgG for quite some time. This is part of how our body remembers previous infections so we can fight them off better if we get them again.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jan 12, 2015

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