Is there a way to be deficient in vitamin b1?

Yes: It' s rare to be deficient in thiamine, but alcoholics, people with crohn' s disease, anorexia, and those undergoing kidney dialysis may be deficient. Symptoms of thiamine deficiency are fatigue, irritability, depression and abdominal discomfort. More acutely, you can see confusion, ataxia, and eye movement paralysis. Without rapid treatment, the person can become comatose, and ultimately die.