What causes dupuytrens?

Thickened fascia: A layer of tissue beneath the skin in the palm becomes abnormally thickened. This thickened tissue can over time contract and cause discomfort and fixed contracture of fingers and especially the middle ring and pinky. As to why this happens in certain individuals, no one really knows though there is some genetic basis. See www.Myhandhealth.Com for more info, click on dupuytrens.

Not entirely known: Some researchers believe that Dupuytren's disease is due to an autoimmune reaction, but other research suggests there is a genetic predisposition. Factors that may increase the risk of palmar fibromatosis including age, sex, ancestry, tobacco use, and disease such as diabetes and epilepsy. Palmar fibromatosis may occur with age, after trauma and from medications and may be unrelated to Dupuytren's

Fibroproliferation: Dupuytren's contracture is a genetically mediated fibroproliferative disorder. There is a proliferation of collagen which leads to subcutaneous nodules and cords. Eventually the cords draw the fingers down to the palm, preventing extension.

Fibromatosis: Dupuytren's is an abnormal fibro-proliferative disorder also called palmar fibromatosis know as vikings disease it has a significant familial and genetic etiology here is a link to some additional ideas on facebook regarding dupuytren's https://www.Facebook.Com/pages/dupuytrens-disease-new-treatment-updates/147337105335050?Ref=hl.

Genetics: Dupuytren's occurs on all races and is considered to be hereditary. It is common in northern europeans over 50 and in men more than women.

Unknown: it is not know what causes it but it has a genetic pre disposition and it is associated with alcoholism, diabetes, epilepsy but not caused by those diseases