A member asked:

How is holoprosencephaly malformation complex caused?

A doctor has provided 1 answer
Dr. Nikolaos Zacharias answered

Specializes in Maternal-Fetal Medicine

Neuronal migration.: Holoprosencephaly is a developmental anomaly typically found in trisomy 13 (patau syndrome) and associated with neuronal migration anomalies resulting in fusion of the cerebral ventricles and hemispheres.

Answered 7/21/2012

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