A member asked:

Blood work results: "elevated rheumatoid factor & ccp c/w ra; elevated jo 1 (34h) & anti histone (1.2h) antibodies, mng" what should this mean to me?

7 doctors weighed in across 2 answers

Rheumatoid factor: Elevated rheumatoid factor and CRP are non-specific but suggest one of the many disorders in the autoimmune, rheumatologic group. Jo 1 antibodies are used to identify the myosites (muscle inflammation) types of disease, and anti-histones can help identify either regular lupus or drug-induced lupus. It used to be thought specific for drug-induced lupus, but it now appreas there is a lot of overlap.

Answered 6/10/2014

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Dr. Aaron Broadwell answered

Specializes in Internal Medicine

See a rheumatologist: The rf and ccp would suggest RA strongly: the jo-1 can go along with polymyositis, but your rheumatologist would need to see if they thought you have that.

Answered 1/4/2018

4.1k views

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