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A 42-year-old member asked:

what are normal results for glycine in cerebrospinal fluid?

1 doctor answer1 doctor weighed in
Dr. William Goldie
Pediatric Neurology 48 years experience
Difficult question: Glycine is an Amino Acid that is the product of normal protein metabolism. Rare cases of inborn errors of metabolism result in a defect in metabolism of certain Amino Acids including glycine. A very rare disorder is non-ketotic hyperglycinemia where the glycine in the CSF is many times normal. The range of normal varies with ingestion of protein and depending on the form of laboratory assay.

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A 36-year-old member asked:

What sort of disorder is CSF otorrhea?

1 doctor answer6 doctors weighed in
Dr. Peter Corrado
Family Medicine 41 years experience
A serious condition: CSF is cerebrospinal fluid, the fluid that surrounds your brain and spinal cord. CSF otorrhea is when the fluid is draining out of your ear. It is considered a sign of a basilar skull fracture. It can also be associated with leakage thru the nose which is refered to as CSF rhinorrhea.
A 30-year-old member asked:

How do you treat CSF otorrhea?

1 doctor answer5 doctors weighed in
Dr. Alan Jacobs
Neurology 32 years experience
It depends: It depends on the cause- basilar skull fracture, recent surgery, congenital, inner ear disease or rarely spontaneously. Also implied is a perforated ear drum allowing the leaking CSF to exit the middle ear into the external ear canal or eustachian tube. Meningitis must be identified if present. Treatment could involve antibiotics, diuretics, steroids or surgery.
A 39-year-old member asked:

My friend got CSF otorrhea. Why is that?

1 doctor answer2 doctors weighed in
Dr. Nikolaos Zacharias
Maternal-Fetal Medicine 26 years experience
Otitis? Trauma?: Complicated otitis can cause lesions in the inner/middle ear that erode through the brain coverings (meninges) threatening meningitis and encephalitis with serious or even lethal consequences. CSF otorrhea can alternatively be the result of tumors of trauma to the base of the skull and is a very serious condition - emergent medical care should be sought with ent, neurosurgery, and neurology.
MO
A 29-year-old male asked:

What would cause the protein to be a little high in spinal fluid?

2 doctor answers4 doctors weighed in
Dr. Masoud Sadighpour
Internal Medicine 38 years experience
High protein: High protein can be elevated in CSF due to infection or inflammation. It is non-specific. Your doctor can tell you based on your history , sign and symptoms.
CA
A 25-year-old female asked:

Can people w/o hydrocephalus have CSF pressure increase or headaches caused by intracranial pressure?

1 doctor answer1 doctor weighed in
Dr. Steven Willing
Radiology 45 years experience
Yes: The condition is called "pseudotumor cerebri" or "benign intracranial hypertension". It occurs most commonly in females between 20 and 40, especially in the overweight or obese. The definitive test is a spinal tap with direct measurement of the fluid pressure.

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Last updated Jun 24, 2014
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