A member asked:

Can benadryl (diphenhydramine) help a swelling and hive reaction (itching) allergic reaction to penicillin?

A doctor has provided 1 answer
Dr. Al Hegab answered

Specializes in Allergy and Immunology

Depends: on the reaction, if just hives and itching, yes benadryl (diphenhydramine) can control it in the right dosage, after discontinuing the offending drug, but if more severe symptoms/swelling you need medical attention with the possible addition of epinephrine and probably steroids,

Answered 11/23/2019

3.3k views

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