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A member asked:

How quickly does venlafaxine start to work for pain ?

A doctor has provided 1 answer
Dr. Miguel Pappolla answered

Specializes in Pain Management

It depends: One to three weeks but it depends on the dose. At a dose of 225 mg per day or more it enhances the descending pain inhibitory pathways by making more norepinephrine available at synaptic sites (communication points between nerve cells).

Answered 1/10/2015

3.3k views

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