It it safe to take some oxaprozin and tramadol at the same time?

Not likely: Not the best choice-they are quite similar: that'd be like taking advil + Aleve together. If you need that much pain relief (and you have no reason not to take tylenol (acetaminophen)), i'd use tylenol (acetaminophen) with 1 or the other for pain relief. Sounds to me like you might need some physical therapy, acupuncture: look up msm, digestive enzymes, & krill oil as anti inflammatories. Hrs, md. www.thepmc.or.