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A 67-year-old female asked:

On a pet scan does a lower suv uptake mean less aggressive cancer ? the suv uptake was 5.2,

1 doctor answer1 doctor weighed in
Dr. John To
Dr. John Toanswered
32 years experience
No: SUV has no bearing on the aggressiveness of the cancer. It is a relative measure of the glucose metabolism. In fact, some very aggressive tumors have no FDG uptake at all. Some benign conditions like infection can have high uptake. The standard uptake value depends on many factors like patient body size and serum glucose level and the normal uptake in the tissue surrounding the target lesion.
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United Kingdom
A 67-year-old female asked:

Is it better that the SUV Max on a pet scan is lower than higher? Does this mean the cancer Is less aggressive and less active What is the highest it can be !

2 doctor answers3 doctors weighed in
Dr. Kris Gast
Radiation Oncology 33 years experience
PET & SUV: most PET scans have a range of SUV that goes from 0 to 4, which is felt to be less likely malignant. The SUV above 4 is more suspicious of cancer. PET scans pick up spots where the tissues are using more energy...like infections, surgery sites, and cancers. There really is no upper limit. If your SUV is declining this usually means the cancer is responding or dying off.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Kris Gast
Dr. Kris Gast commented
Radiation Oncology 33 years experience
Provided original answer
Happy to help. Best of luck
Dec 31, 2014
Last updated Feb 26, 2021

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